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LABORATORY TEST DIRECTORY

BRAF Codon 600 Mutation Detection with Reflex to MLH1 Promoter Methylation

CPT Code(s): 88381; 81210; If reflexed, add 81288
Specimen Required: Patient Preparation:
Collect:Tumor tissue.
Specimen Preparation:Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Tissue block will be returned after testing.Transport tissue block or 5 unstained 5-micron slides in a tissue transport kit (RDL supply #47808) available online through eSupply using RDL Connectâ„¢ or contact RDL Client Services at (888) 431-7474. (Min: 3 slides). Protect paraffin block and/or slides from excessive heat.
Storage/Transport Temperature:Room temperature or refrigerated. Ship in cooled container during summer months.
Stability:Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
New York DOH Approval Status: This test is New York DOH approved.
Aliases:
  • BRAF Gene Mutation Assay
  • EGFR targeted therapy
  • BRAF Mutation Analysis
  • MLH1sporadic Lynch SyndromeV600E